Modafinil 200 mg Australia is a wake-promoting medication used to treat narcolepsy. It is also widely use as a cognitive enhancer for boosting alertness and performance.
In two 9-week, large-scale, double-blind placebo-control trials with Modafinil 200 mg Australia once daily. It has been show to improve performance on various cognitive tasks.
Before taking Modafinil, tell your doctor if you have high blood pressure or heart problems (e.g., a history of heart attack or a heart valve problem). Liver disease, mental/mood disorders (e.g., depression, mania), or personal or family history of addiction to drugs/alcohol.
Effects
In a randomized, double-blind, placebo-controlled study of emergency department residents and attending physicians. Modafinil 200 mg Australia increased certain aspects of cognitive function but did not prevent sleep induction or improve participants’ ability to attend post-nightshift didactic classroom sessions. The results were similar to those observed in another 9-week, large-scale, clinical trial that used a higher dose of 400 mg per day. The studies were conducted at Brookhaven National Laboratory and approved by the local institutional review board (Committee on Research Involving Human Subjects, State University of New York at Stony Brook). The participants received written informed consent before participating.
Modafinil increases subjective alertness and objective performance to a degree comparable to that of caffeine in the morning after at least 40 h of sleep loss. It also reduces subjective sleepiness but does not affect the time to fall asleep or total sleep time. Unlike some psycho-stimulants, Modafinil does not significantly impair objective performance during the afternoon following administration and does not cause rebound hypersomnolence. Firm studies show that Modafinil reduces amygdale activity during the processing of fearful faces, but does not alter conditioned taste aversion learning. This suggests that Modafinil does not exhibit a Yerkes-Dodson effect, but may have other mechanisms of action.
Plasma [11C]raclopride and [11C]cocaine BPND were measured by microdialysis before and 2 hours after Modafinil or placebo (corresponding to scan initiation). Repeated-measures analysis of variance revealed a significant Modafinil effect in both the caudate and putamen, but not in the nucleus acumens. Modafinil decreased mean BPND for both radiotracers. But the method of measurement does not allow the exclusion of the possibility that these decreases reflect down-regulation of D2 and D3 dopamine receptors or changes in affinity39 rather than an increase in extracellular dopamine.
Behavioral effects were evaluate using analog scales and the Profile of Mood Scales. A widely use self-report measure of mood states ranging from 1 (“not at all”) to 10 (“extremely”). Heart rate and systolic blood pressure were monitor continuously throughout the study.
Dosage
Modafinil 200 mg Australia is a wake-promoting medication that is use to treat excessive daytime sleepiness associated with disorders such as narcolepsy, shift work disorder, and obstructive sleep apnea. It has also been use to improve mental alertness and performance in patients with certain brain disorders. It acts as a psycho-stimulant but has a mechanism of action that is distinct from classical psycho-stimulants. Modafinil affects noradrenergic, dopaminergic (specifically, the dopamine transporter), and GABAergic systems, as well as histaminergic and hypocretin systems.
In multiple clinical trials, Modafinil has been show to improve fatigue and vigilance in several conditions such as narcolepsy, obstructive sleep apnea, and shift work disorder. It is also effective in reducing symptoms of MS-related fatigue, including those associated with fatigue caused by MS flares. In addition, once-daily Modalert 200 buy online has been find to be a highly effective treatment for ADHD.
Unlike some other stimulants, Modafinil does not increase heart rate and blood pressure. However, it may cause a few minor side effects such as headache, stomach upset, and dizziness. Some people also experience a skin rash, although this is less common. Do not share this medication with others. Modafinil can be habit-forming and should only be use by the person for whom it was prescribe.
It may harm an unborn baby or can be harmful to a nursing infant. It is unknown if this medication passes into breast milk, so consult your doctor before breastfeeding. If you are using this medication, let your doctor know if you have a history of mental illness or bipolar disorder. Symptoms of depression, hallucinations, or suicidal thoughts are possible in some people taking this medication. Your doctor will closely monitor you for these side effects.
Modafinil can be abuse by people looking for an artificial “buzz”. It is illegal to possess and sell in some jurisdictions, and possession for personal use can result in jail time of up to seven years. It is also considerea a doping agent and has been use by athletes to enhance their performance. Consequently, it is strictly prohibit in sports competitions.
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